PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in. Medscape – Indication-specific dosing for Durezol, (difluprednate), frequency- based contraindications, pregnancy & lactation schedules, and cost information. Medscape prescription drug monographs are based on FDA- approved labeling. USP) tablets. Full Prescribing Information, including Boxed WARNING Durezol. (difluprednate ophthalmic emulsion) %. Full Prescribing Information. E.

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Store at room temperature between 15 and 25 degrees Prescribinng 59 and 77 degrees F. This list may not describe all possible interactions. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use. You are not eligible if prescriptions are paid by any federal or state program, or where prohibited by law; and you will otherwise comply with the terms and conditions above.

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Instill 1 drop into the conjunctival sac of the affected eye s 4 times daily for 14 days followed by tapering as clinically indicated. Difluprednate has not been studied during breast feeding.

Difluprednate should be used with caution in patients with a corneal abrasion. Account Sign up Login Forgot password.

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Home Shopping cart Checkout Articles. Bacterial infections — Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections.

Additional terms and conditions may apply. Intraocular pressure should incormation monitored after 10 days of therapy, and an ophthalmologic exam should occur after 14 days of therapy. For the treatment of endogenous anterior uveitis, instill one drop into the conjunctival sac of the affected eye 4 times daily for 14 days followed by tapering informationn clinically indicated.


Do not take by mouth.

Fungal invasion should be evaluated in any persistent corneal ulceration where corticosteroid treatment has been used. Corticosteroids inhibit the inflammatory response to a variety of inciting agents and probably delay or slow healing. Use of website is governed by the Terms of Use and Infomration Policy.

Fungal infection, herpes simplex keratitis dendritic keratitismycobacterial infection, ocular infection, varicella, viral infection. In patients with corneal or scleral thinning, administration of topical ophthalmic corticosteroids has caused perforations.

Throw away any unused medicine after the expiration date. Best regards, [Name] Hi, I have just discovered this website and I think it might interest you. Other corticosteroids have been shown to cause fetal resorptions and malformations.

Difluprednate is also contraindicated in any mycobacterial infection of the eye or fungal infection of ocular structures. Related Drug Information Drug Summary.

You certify responsibility for complying with applicable limitations, if any, of any commercial insurance and reporting receipt of program rewards, if necessary, to any commercial insurer.

Call your doctor for medical advice about side effects.

Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition. Ask your doctor or health care professional when you can start wearing your contact lenses again. While the American Academy of Pediatrics does not comment on the use of ophthalmic difluprednate during breast-feeding, it does consider some systemic corticosteroids prednisone and prednisolone to be usually compatible with breast-feeding.


Call if you have any questions. Viral infections — Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex prescribig great caution. The systemic absorption of difluprednate following ophthalmic administration is minimal; however, according to the manufacturer, because there have been no adequate studies conducted into the safe use of difluprednate in pregnant women, it should only be used when the potential benefits informatio the mother outweigh possible risks to the fetus.

Glaucoma, increased intraocular pressure, open-angle glaucoma. See Program Terms and Conditions below. As with all ophthalmic preparations containing a preservative, patients should be advised not to wear contact lenses when using Durezol. To further minimize the amount of drug that reaches the systemic circulation and breast milk, apply pressure over the tear duct by the corner of the eye for 1 minute after ophthalmic administration.

One Therapy for Many Eyes

Delayed healing — The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation. Your message Hi, I have just discovered this website and I think it might interest you. The use of ocular steroids may prolong the course and exacerbate the severity of ocular infections.